Cord blood (Family research)
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Pregunta
I am currently 8 months pregnant. My nephew has CdLS. Can he benefit from my cord blood? Could the cord blood be donated to the research of CdLS, even if there is currently no benefit to a specific individual?
Respuesta de nuestros expertos
In response to your generous offer to donate some cord blood at the time of your pending delivery, there are really 2 issues: 1) Is there any benefit that can be derived from the cord blood itself in terms of potential future therapies or isolation of stem cells from this sample that would benefit your family member with CdLS? At this time there is no known benefit to your family member with CdLS. Currently banking stem cells from cord blood is used primarily to benefit the child that results from the pregnancy in the rare chance that they may need them for therapies related to certain cancers or chemotherapies (e.g. repopulating the bone marrow after treatment for leukemia) - it is hard to know the value of doing this given the rarity of these types of diagnoses and the decision is usually made based on the cost of doing the storage and the potential for needing the stem cells. It is hard to predict what the future will hold in terms of advances in therapeutics for individuals with CdLS, however at this time there is nothing on the immediate horizon that I am aware of that would use stem cells for treatment. 2) Is there any benefit in having a cord blood (or any blood sample) from relatives of an individual with CdLS to help in the research efforts towards identifying the underlying cause? The answer to this is a qualified "yes", but in those families where there are more than one affected individual with CdLS. We routinely ask for samples from parents of children with CdLS because this helps us to see if a change identified in the child with CdLS is a new change or something that was passed on from the parent. With the identification of multiple genes that result in CdLS when changed ("mutated") we now know that 98% of individuals with CdLS have it as a new (or "de novo") change in the gene and as thus is not inherited from a parent. In that small percent in which CdLS is inherited from a mildly affected parent then it is useful to have samples from immediate and sometimes, second degree relatives, for us to both understand identified changes in the gene as well as to identify new causative genes in those families in which a mutation in one of the known genes has not been found.
IK /TK 7-13-10
Failed to execute the [velocity] macro. Cause: [null]. Click on this message for details.
org.xwiki.rendering.macro.MacroExecutionException: Failed to evaluate Velocity Macro for content [{{html}}
##------------------------------------------------------------------------------------
## WaihonaPedia has a Topic-tag model
## the idea is like the xwiki-tag model, but the difference that you can only tag with predefined Topics
## Below we show these tags
## and when context.user is a moderator we offer some edit functionality
##------------------------------------------------------------------------------------
## Refactored "Read More Like This" Logic
#set($topicClassName = "WaihonaCode.pageTopicTagClass")
#set($storyClassName = 'WaihonaCode.themeRoomCloserLookClass')
#set($atePublicClassName = 'WaihonaCode.ATEPublic.ATEPublicClass')
## Predefine the class and query for topic descriptions
#set($topicDescriptionClassName = 'WaihonaCode.healthTopicsClass')
#set($articleClasses = [$storyClassName, $atePublicClassName])
#set($articleTypes = {
"stories": $storyClassName,
"answers": $atePublicClassName,
"information": $topicClassName
})
## Define the sheet mapping for index displayers
#set($articleTypeIndexSheets = {
"stories": "WaihonaCode.publicInfo.storyDisplayer",
"answers": "ATEPublic.topicATEDisplayer",
"information": "WaihonaCode.publicInfo.infoDisplayer"
})
#set($topicTagQueryDef = "from doc.object($topicClassName) as topicTag where topicTag.topicKey = :key")
#set($storyQueryDef = "from doc.object($storyClassName) as story where story.storyTopicKey = :key")
#set($topicDescriptionQueryDef = "from doc.object($topicDescriptionClassName) as topic where topic.key = :thisKey")
## Step 1: Collect unique topicKeys for the current page
#set($topicKeys = [])
## Collect topicKeys from WaihonaCode.pageTopicTagClass
#set($classKeys = [])
#foreach($topicObject in $doc.getObjects($topicClassName, "topicType", "2"))
#if($topicObject.getProperty("topicKey").getValue())
#set($discard = $classKeys.add($topicObject.getProperty("topicKey").getValue()))
#end
#end
#set($topicKeys = $collectiontool.union($topicKeys, $classKeys))
## Collect topicKeys from article-specific classes
#set($articleKeys = [])
#foreach($className in $articleClasses)
#if($doc.getObject($className) && $doc.getObject($className).getProperty("storyTopicKey").getValue() != '')
#set($discard = $articleKeys.add($doc.getObject($className).getProperty("storyTopicKey").getValue()))
#end
#end
#set($topicKeys = $collectiontool.union($topicKeys, $articleKeys))
#if($doc.getObject($atePublicClassName))
#set($ateTopicKeys = [])
#getATETopicTags($ateTopicKeys)
#set($topicKeys = $collectiontool.union($topicKeys, $ateTopicKeys))
#end
## Define the disease-based root path (adjust dynamically for the current disease)
## Assume that the list of topicKeys point a the collection of diseases
## But currently ONE artike is linked to maximum of ONE dsisease, so we can safely break after ONE
#set($diseaseLibraryBasePath = '')
#foreach($thisKey in $topicKeys)
#getDiseaseWithTopic($thisKey, $diseaseLibraryBasePath)
#break
#end
#if($diseaseLibraryBasePath != '')
#set($diseaseLibraryDoc = $xwiki.getDocument($diseaseLibraryBasePath))
#end
## Step 2: Query and count articles by type for each topicKey
#set($tagData = {}) ## Structure: { topicKey: {type: count} }
#set($currentDocRef = $doc.getDocumentReference())
#foreach($key in $topicKeys)
#set($typeCounts = {})
#set($storyDocRefArray = [])
#set($ateDocRefArray = [])
#foreach($type in $articleTypes.keySet())
#set($className = $articleTypes.get($type))
#set($typeCount = 0)
## Dynamic query based on article type
#if($className == $storyClassName)
## For Patient story type, use storyTopicKey
#set($articlesHavingStoryClassList = $services.query.xwql($storyQueryDef).bindValue("key", $key).addFilter("unique").execute())
#foreach($articlesHavingStoryDocRef in $articlesHavingStoryClassList)
#if($xwiki.getDocument($articlesHavingStoryDocRef).getDocumentReference() != $currentDocRef)## Avoid double count
#set($typeCount = $typeCount + 1)
#set($discard = $storyDocRefArray.add($articlesHavingStoryDocRef))## to be able to filter topicTag Query
#end
#end
## For other types, loop through a list of pages with topicTagObjects
#set($potentialStoryDocRefList = $services.query.xwql($topicTagQueryDef).bindValue("key", $key).addFilter("unique").execute())
#foreach($potentialStoryDocRef in $potentialStoryDocRefList)
#if($xwiki.getDocument($potentialStoryDocRef).getObject($className)
&& !$storyDocRefArray.contains($potentialStoryDocRef))
#if($xwiki.getDocument($potentialStoryDocRef).getDocumentReference() != $currentDocRef)## Avoid double count
#set($discard = $storyDocRefArray.add($potentialStoryDocRef))
#set($typeCount = $typeCount + 1)
#end
#end
#end
#else
## For other types, loop through a list of pages with topicTagObjects
#set($otherTypeDocRefList = $services.query.xwql($topicTagQueryDef).bindValue("key", $key).addFilter("unique").execute())
#set($typeCount = 0)
## Issue with count of Expert Articles, example WaihonaPediaThemes.cdls0.cdls0sub2 counts 2 expert articles while there is only 1?
#foreach($otherTypeDocRef in $otherTypeDocRefList)
#if($xwiki.getDocument($otherTypeDocRef).getObject($className))
#if($xwiki.getDocument($otherTypeDocRef).getDocumentReference() != $currentDocRef) ## Avoid double count
## Issue with ATEPublic articles, on the number found seems still to double count because of translation issue
#if($className == $atePublicClassName)
#set($discard = $ateDocRefArray.add($otherTypeDocRef))
#set($typeCount = $typeCount + 1)
#else
#if(!$ateDocRefArray.contains($otherTypeDocRef)
&& !$storyDocRefArray.contains($otherTypeDocRef))
#set($typeCount = $typeCount + 1)
#end
#end##$className == $atePublicClassName
#end## Avoid double count
#end##class name
#end
#end
#set($discard = $typeCounts.put($type, $typeCount))
#end
## Calculate total count manually
#set($totalCount = 0)
#foreach($count in $typeCounts.values())
#set($totalCount = $totalCount + $count)
#end
## Add typeCounts to tagData if there is at least one non-zero count
#if($totalCount > 0)
#set($discard = $tagData.put($key, $typeCounts))
#end
#end
## Step 3: Render tags if article count > 0
#if($tagData.size() > 0)
<div class='meta-topics'>
<span class='meta-topics-label'>$services.localization.render('waihonapedia.meta.topics.title')</span>
<span class="topics-with-page">
#foreach($entry in $tagData.entrySet())
#set($key = $entry.key)
#set($typeCounts = $entry.value)
## Fetch the localized description for the current topicKey
#set($topicDescription = "")
#set($topicDescriptionList = $services.query.xwql($topicDescriptionQueryDef).bindValue('thisKey', $key).addFilter('unique').execute())
#foreach($topicDescriptionDocRef in $topicDescriptionList)
#set($topicDescriptionDoc = $xwiki.getDocument($topicDescriptionDocRef))
#set($topicDescription = $topicDescriptionDoc.getTranslatedDocument().getPlainTitle())
#end
## Iterate through each type and count
#foreach($type in $articleTypes.keySet())
#if($typeCounts.get($type) > 0)
## Construct the index page URL dynamically
#set($indexSheet = $articleTypeIndexSheets.get($type))
#set($indexURL = $diseaseLibraryDoc.getURL('view', "sheet=${indexSheet}&topic=${key}"))
<span class="label topic-link">
<a href="$indexURL">
<span class='wai-tile-icon-area'>
<span class="wai-tile-icon waihonapedia-${type}" style='width: 1.25em; height: 1.25em;'> </span>
</span> $topicDescription <span class='badge badge-light'>${typeCounts.get($type)}</span>
</a>
</span>
#end
#end
#end
</span>
</div>
#end
#macro(getDiseaseWithTopic $thisTopicKey, $diseaseLibraryBasePath)
##titi $thisTopicKey
#set($diseaseClassName = 'WaihonaCode.diseaseClass')
#set($diseaseTagClassName = 'WaihonaCode.ATEPublic.diseaseTagClass')
#set($topicClassName = 'WaihonaCode.healthTopicsClass')
#set($topicQueryByKeyDef = "from doc.object($topicClassName) as topic where topic.key = :thisTopicKey")
#set($topicQueryByParentKeyDef = "from doc.object($topicClassName) as topic where topic.parent = :thisParentKey")
#set($diseaseByKeyQueryDef = "from doc.object($diseaseClassName) as disease where disease.key = :diseaseKey")
##
#if($thisTopicKey && $thisTopicKey != '')
#set($topicDocRefByKeyList = $services.query.xwql($topicQueryByKeyDef).bindValue("thisTopicKey", $thisTopicKey ).addFilter("unique").execute())
#end
#foreach($topicDocRef in $topicDocRefByKeyList)
#set($topicDoc = $xwiki.getDocument($topicDocRef) )
#if(!$topicDoc.getObject($diseaseTagClassName))
#set($diseaseObject = {})
#getDisease($thisTopicKey, $diseaseObject)
#if($diseaseObject.key && $diseaseObject.key !='')
#set($diseaseDocRefByKeyList = $services.query.xwql($diseaseByKeyQueryDef).bindValue("diseaseKey", $diseaseObject.key ).addFilter("unique").execute())
#else
#set($diseaseDocRefByKeyList = [])
#end
#foreach($diseaseDocRef in $diseaseDocRefByKeyList)
#set($diseaseDoc = $xwiki.getDocument($diseaseDocRef))
#set($diseaseLibraryBasePath = $diseaseDoc.getObject($diseaseClassName).getProperty('publicationspace').getValue())
#end
#else
#set($diseaseKey = $topicDoc.getObject($diseaseTagClassName).getProperty('diseaseKey').getValue() )
#set($diseaseDocRefByKeyList = $services.query.xwql($diseaseByKeyQueryDef).bindValue("diseaseKey", $diseaseKey ).addFilter("unique").execute())
#foreach($diseaseDocRef in $diseaseDocRefByKeyList)
#set($diseaseDoc = $xwiki.getDocument($diseaseDocRef))
#set($diseaseLibraryBasePath = $diseaseDoc.getObject($diseaseClassName).getProperty('publicationspace').getValue())
#end
#end
#end
#end
#macro(getATETopicTags)
#set($ateQuestionParentQueryDef = "from doc.object($atePublicClassName) as qa where qa.questionID = :questionID")
#set($ateQuestionTranslationsQueryDef = "from doc.object($atePublicClassName) as qa where qa.parentQuestionID = :questionID")
## Step 1: Identify Translations of the Current Page
#set($relatedPages = [])
##if($doc.getObject($atePublicClassName))
## Check if this is a translated page (has 'parentQuestionID')
#set($parentQuestionID = $doc.getObject($atePublicClassName).getProperty('parentQuestionID').getValue())
#set($questionID = $doc.getObject($atePublicClassName).getProperty('questionID').getValue())
#if($parentQuestionID)
## Fetch the original page (parent of the translation)
#set($originalPageList = $services.query.xwql($ateQuestionParentQueryDef).bindValue('questionID', $parentQuestionID).addFilter('unique').execute())
#set($relatedPages = $collectiontool.union($relatedPages, $originalPageList))
#elseif($questionID)
## Fetch all translations of this page
#set($translationPageList = $services.query.xwql($ateQuestionTranslationsQueryDef).bindValue('questionID', $questionID).addFilter('unique').execute())
#set($relatedPages = $collectiontool.union($relatedPages, $translationPageList))
#end
## Add the current page to the relatedPages
#set($currentPageRef = $doc.getDocumentReference())
#if(!$relatedPages.contains($currentPageRef))
#set($discard = $relatedPages.add($currentPageRef))
#end
## Step 2: Collect TopicTags from All Related Pages
#set($aggregatedTopicKeys = [])
#foreach($pageRef in $relatedPages)
#set($relatedDoc = $xwiki.getDocument($pageRef))
#foreach($topicObject in $relatedDoc.getObjects($topicClassName, "topicType", "2"))
#if($topicObject.getProperty("topicKey").getValue())
#set($discard = $aggregatedTopicKeys.add($topicObject.getProperty("topicKey").getValue()))
#end
#end
#end
## Ensure Unique TopicKeys Manually
#set($uniqueTopicKeysMap = {})
#foreach($topicKey in $aggregatedTopicKeys)
#if(!$uniqueTopicKeysMap.containsKey($topicKey))
#set($discard = $uniqueTopicKeysMap.put($topicKey, true))
#end
#end
## Convert the Map keys back to a list
#foreach($key in $uniqueTopicKeysMap.keySet())
#set($discard = $ateTopicKeys.add($key))
#end
#end
#macro(getDisease $thisTopicKey $diseaseObject)
#set($maxDepth = 10)
#set($range = [0..$maxDepth])
#set($currentKey = $thisTopicKey)
#set($found = false)
#foreach($i in $range)
#if($found || !$currentKey)
#break()
#end
## Your logic here, e.g., querying with $currentKey
#set($topicDocList = $services.query.xwql($topicQueryByKeyDef).bindValue('thisTopicKey', $currentKey).addFilter('unique').execute())
#if($topicDocList.size() > 0)
#foreach($topicDocRef in $topicDocList)
#set($topicDoc = $xwiki.getDocument($topicDocRef))
#if($topicDoc.getObject($diseaseTagClassName))
#set($found = true)
#toplevelTopic($topicDoc.documentReference $diseaseObject)
#else
#set($topicObj = $topicDoc.getObject($topicClassName))
#set($currentKey = $topicObj.getProperty('parent').getValue())
#end
#end
#else
#set($currentKey = '')
#end
#end
#end
#macro(toplevelTopic $topicTopLevelDocRef $diseaseObject)
#set($diseaseKey = $xwiki.getDocument($topicTopLevelDocRef).getObject($diseaseTagClassName).getProperty('diseaseKey').getValue() )
#if($diseaseKey && $diseaseKey != '')
#set($discard = $diseaseObject.put('key', $diseaseKey))
#set($diseaseClassName = 'WaihonaCode.diseaseClass')
#set($diseaseQueryDef = "from doc.object($diseaseClassName) as dis where dis.key = :thisKey")
#set($diseaseDocList = $services.query.xwql($diseaseQueryDef).bindValue('thisKey', $diseaseKey).addFilter('unique').execute() )
#foreach($diseaseDocRef in $diseaseDocList)
#set($thisTitle = $xwiki.getDocument($diseaseDocRef).getTranslatedDocument().getPlainTitle())
#set($thisContent = $xwiki.getDocument($diseaseDocRef).getTranslatedContent() )
#end
#else
#set($thisTitle = "unknown syndrome on $xwiki.getDocument($topicTopLevelDocRef).getPlainTitle()")
#set($thisContent = '' )
#end
#set($discard = $diseaseObject.put('title', $thisTitle) )
#set($discard = $diseaseObject.put('content', $thisContent) )
#end
{{/html}}]
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:186)
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:60)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.evaluateBlock(AbstractScriptMacro.java:279)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.execute(AbstractScriptMacro.java:182)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.execute(AbstractScriptMacro.java:58)
at org.xwiki.rendering.internal.transformation.macro.MacroTransformation.transform(MacroTransformation.java:441)
at org.xwiki.rendering.internal.transformation.DefaultRenderingContext.transformInContext(DefaultRenderingContext.java:183)
at org.xwiki.rendering.async.internal.block.AbstractBlockAsyncRenderer.transform(AbstractBlockAsyncRenderer.java:76)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRenderer.tranform(DefaultBlockAsyncRenderer.java:154)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRenderer.execute(DefaultBlockAsyncRenderer.java:137)
at org.xwiki.rendering.async.internal.block.AbstractBlockAsyncRenderer.render(AbstractBlockAsyncRenderer.java:157)
at org.xwiki.uiextension.internal.WikiUIExtension.render(WikiUIExtension.java:201)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor$DecoratorWrapper.render(DefaultBlockAsyncRendererExecutor.java:67)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor$DecoratorWrapper.render(DefaultBlockAsyncRendererExecutor.java:49)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.execute(DefaultBlockAsyncRendererExecutor.java:125)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.execute(DefaultBlockAsyncRendererExecutor.java:113)
at org.xwiki.uiextension.internal.AbstractWikiUIExtension.execute(AbstractWikiUIExtension.java:101)
at org.xwiki.uiextension.internal.AbstractWikiUIExtension.execute(AbstractWikiUIExtension.java:89)
at jdk.internal.reflect.GeneratedMethodAccessor411.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:569)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.value(ASTReference.java:704)
at org.apache.velocity.runtime.parser.node.ASTExpression.value(ASTExpression.java:75)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:167)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:190)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.InternalVelocityEngine.evaluate(InternalVelocityEngine.java:233)
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:168)
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:60)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.evaluateBlock(AbstractScriptMacro.java:279)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.execute(AbstractScriptMacro.java:182)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.execute(AbstractScriptMacro.java:58)
at org.xwiki.rendering.internal.transformation.macro.MacroTransformation.transform(MacroTransformation.java:441)
at org.xwiki.rendering.internal.transformation.DefaultRenderingContext.transformInContext(DefaultRenderingContext.java:183)
at org.xwiki.rendering.internal.transformation.DefaultTransformationManager.performTransformations(DefaultTransformationManager.java:88)
at org.xwiki.display.internal.DocumentContentAsyncExecutor.executeInCurrentExecutionContext(DocumentContentAsyncExecutor.java:396)
at org.xwiki.display.internal.DocumentContentAsyncExecutor.execute(DocumentContentAsyncExecutor.java:269)
at org.xwiki.display.internal.DocumentContentAsyncRenderer.execute(DocumentContentAsyncRenderer.java:112)
at org.xwiki.rendering.async.internal.block.AbstractBlockAsyncRenderer.render(AbstractBlockAsyncRenderer.java:157)
at org.xwiki.rendering.async.internal.block.AbstractBlockAsyncRenderer.render(AbstractBlockAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:290)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.execute(DefaultBlockAsyncRendererExecutor.java:125)
at org.xwiki.display.internal.DocumentContentDisplayer.display(DocumentContentDisplayer.java:93)
at org.xwiki.display.internal.DocumentContentDisplayer.display(DocumentContentDisplayer.java:46)
at org.xwiki.display.internal.DefaultDocumentDisplayer.display(DefaultDocumentDisplayer.java:96)
at org.xwiki.display.internal.DefaultDocumentDisplayer.display(DefaultDocumentDisplayer.java:39)
at org.xwiki.sheet.internal.SheetDocumentDisplayer.display(SheetDocumentDisplayer.java:245)
at org.xwiki.sheet.internal.SheetDocumentDisplayer.applySheet(SheetDocumentDisplayer.java:225)
at org.xwiki.sheet.internal.SheetDocumentDisplayer.maybeDisplayWithSheet(SheetDocumentDisplayer.java:180)
at org.xwiki.sheet.internal.SheetDocumentDisplayer.display(SheetDocumentDisplayer.java:111)
at org.xwiki.sheet.internal.SheetDocumentDisplayer.display(SheetDocumentDisplayer.java:52)
at org.xwiki.display.internal.ConfiguredDocumentDisplayer.display(ConfiguredDocumentDisplayer.java:68)
at org.xwiki.display.internal.ConfiguredDocumentDisplayer.display(ConfiguredDocumentDisplayer.java:42)
at com.xpn.xwiki.doc.XWikiDocument.display(XWikiDocument.java:1431)
at com.xpn.xwiki.doc.XWikiDocument.getRenderedContent(XWikiDocument.java:1567)
at com.xpn.xwiki.doc.XWikiDocument.displayDocument(XWikiDocument.java:1517)
at com.xpn.xwiki.doc.XWikiDocument.displayDocument(XWikiDocument.java:1486)
at com.xpn.xwiki.api.Document.displayDocument(Document.java:821)
at jdk.internal.reflect.GeneratedMethodAccessor455.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:569)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.value(ASTReference.java:704)
at org.apache.velocity.runtime.parser.node.ASTExpression.value(ASTExpression.java:75)
at org.apache.velocity.runtime.parser.node.ASTSetDirective.render(ASTSetDirective.java:242)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:190)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.xwiki.velocity.internal.directive.TryCatchDirective.render(TryCatchDirective.java:86)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.InternalVelocityEngine.evaluate(InternalVelocityEngine.java:233)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:107)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:219)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:174)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:135)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:907)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:869)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:856)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:811)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:803)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:79)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:73)
at org.xwiki.template.script.TemplateScriptService.render(TemplateScriptService.java:54)
at jdk.internal.reflect.GeneratedMethodAccessor252.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:569)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:217)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.InternalVelocityEngine.evaluate(InternalVelocityEngine.java:233)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:107)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:219)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:174)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:135)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:907)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:869)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:856)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:811)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:803)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:79)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:73)
at org.xwiki.template.script.TemplateScriptService.render(TemplateScriptService.java:54)
at jdk.internal.reflect.GeneratedMethodAccessor252.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:569)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:217)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:190)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.InternalVelocityEngine.evaluate(InternalVelocityEngine.java:233)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:107)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:219)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:174)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:135)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:907)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:869)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:849)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:835)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.render(DefaultTemplateManager.java:91)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.render(DefaultTemplateManager.java:85)
at com.xpn.xwiki.XWiki.evaluateTemplate(XWiki.java:2569)
at com.xpn.xwiki.web.Utils.parseTemplate(Utils.java:180)
at com.xpn.xwiki.web.XWikiAction.execute(XWikiAction.java:651)
at com.xpn.xwiki.web.XWikiAction.execute(XWikiAction.java:339)
at com.xpn.xwiki.web.LegacyActionServlet.service(LegacyActionServlet.java:108)
at javax.servlet.http.HttpServlet.service(HttpServlet.java:623)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:199)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at com.xpn.xwiki.web.ActionFilter.doFilter(ActionFilter.java:122)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.xwiki.wysiwyg.filter.ConversionFilter.doFilter(ConversionFilter.java:61)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:51)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.xwiki.container.servlet.filters.internal.SetHTTPHeaderFilter.doFilter(SetHTTPHeaderFilter.java:63)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.xwiki.resource.servlet.RoutingFilter.doFilter(RoutingFilter.java:132)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.xwiki.container.servlet.filters.internal.SavedRequestRestorerFilter.doFilter(SavedRequestRestorerFilter.java:209)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.xwiki.container.servlet.filters.internal.SetCharacterEncodingFilter.doFilter(SetCharacterEncodingFilter.java:117)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:168)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:144)
at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:168)
at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:90)
at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:482)
at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:130)
at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:93)
at org.apache.catalina.valves.AbstractAccessLogValve.invoke(AbstractAccessLogValve.java:656)
at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:74)
at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:346)
at org.apache.coyote.http11.Http11Processor.service(Http11Processor.java:397)
at org.apache.coyote.AbstractProcessorLight.process(AbstractProcessorLight.java:63)
at org.apache.coyote.AbstractProtocol$ConnectionHandler.process(AbstractProtocol.java:935)
at org.apache.tomcat.util.net.NioEndpoint$SocketProcessor.doRun(NioEndpoint.java:1826)
at org.apache.tomcat.util.net.SocketProcessorBase.run(SocketProcessorBase.java:52)
at org.apache.tomcat.util.threads.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1189)
at org.apache.tomcat.util.threads.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:658)
at org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:63)
at java.base/java.lang.Thread.run(Thread.java:840)
Caused by: org.xwiki.velocity.XWikiVelocityException: Failed to evaluate content with namespace [xwiki:WaihonaBase.uixCollections.contentFooter.waiTopicTagsUIX-2^XWiki.UIExtensionClass[0]]
at org.xwiki.velocity.internal.InternalVelocityEngine.evaluate(InternalVelocityEngine.java:235)
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:168)
... 235 more
Caused by: org.apache.velocity.exception.MethodInvocationException: Invocation of method 'execute' in class org.xwiki.query.internal.ScriptQuery threw exception org.xwiki.query.QueryException: Exception while executing query. Query statement = [ select doc.fullName from XWikiDocument as doc , BaseObject as story , com.xpn.xwiki.objects.StringProperty as story_storyTopicKey1 where ( story_storyTopicKey1.value = :key ) and doc.fullName=story.name and story.className='WaihonaCode.themeRoomCloserLookClass' and story_storyTopicKey1.id.id=story.id and story_storyTopicKey1.id.name='storyTopicKey' ] at xwiki:WaihonaBase.uixCollections.contentFooter.waiTopicTagsUIX-2[line 82, column 118]
at org.apache.velocity.runtime.parser.node.ASTMethod.handleInvocationException(ASTMethod.java:308)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:235)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.value(ASTReference.java:704)
at org.apache.velocity.runtime.parser.node.ASTExpression.value(ASTExpression.java:75)
at org.apache.velocity.runtime.parser.node.ASTSetDirective.render(ASTSetDirective.java:242)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.InternalVelocityEngine.evaluate(InternalVelocityEngine.java:233)
... 236 more
Caused by: org.xwiki.query.QueryException: Exception while executing query. Query statement = [ select doc.fullName from XWikiDocument as doc , BaseObject as story , com.xpn.xwiki.objects.StringProperty as story_storyTopicKey1 where ( story_storyTopicKey1.value = :key ) and doc.fullName=story.name and story.className='WaihonaCode.themeRoomCloserLookClass' and story_storyTopicKey1.id.id=story.id and story_storyTopicKey1.id.name='storyTopicKey' ]
at com.xpn.xwiki.store.hibernate.query.HqlQueryExecutor.execute(HqlQueryExecutor.java:222)
at org.xwiki.query.internal.DefaultQueryExecutorManager.execute(DefaultQueryExecutorManager.java:72)
at org.xwiki.query.internal.DefaultQuery.execute(DefaultQuery.java:306)
at org.xwiki.query.xwql.internal.XWQLQueryExecutor.execute(XWQLQueryExecutor.java:117)
at org.xwiki.query.internal.DefaultQueryExecutorManager.execute(DefaultQueryExecutorManager.java:72)
at org.xwiki.query.internal.SecureQueryExecutorManager.execute(SecureQueryExecutorManager.java:67)
at org.xwiki.query.internal.DefaultQuery.execute(DefaultQuery.java:306)
at org.xwiki.query.internal.ScriptQuery.execute(ScriptQuery.java:278)
at jdk.internal.reflect.GeneratedMethodAccessor282.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:569)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
... 254 more
Caused by: com.xpn.xwiki.XWikiException: Error number 0 in 3: Exception while hibernate execute
at com.xpn.xwiki.store.XWikiHibernateBaseStore.execute(XWikiHibernateBaseStore.java:835)
at com.xpn.xwiki.store.XWikiHibernateBaseStore.executeRead(XWikiHibernateBaseStore.java:902)
at com.xpn.xwiki.store.hibernate.query.HqlQueryExecutor.execute(HqlQueryExecutor.java:207)
... 267 more
Caused by: java.lang.NullPointerException
Recomendación (es)
diagnóstico prenatal (antes del nacimiento) de SCdL
Aviso legal
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