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Heredity and level of affectedness with CdLS

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Question

What are the possibilities for an individual with CdLS to have a child with CdLS? If they do, will that child most likely show a similar level of affectedness?

Answer of our experts

Individuals with CdLS are likely to be the more mildly affected if they are able to achieve reproduction. This type is thought to be due to a dominant gene. This means that the individual with CdLS has a 50% chance, in each reproductive event, to have a child with CdLS. The child may be similarly affected or more severely affected than the parent. LJ (4-10-01) Most individuals with CdLS should be considered to be fertile, unless a male with undescended testicles. Females need to be protected if in an unsupervised situation

TK 7-13-10

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Recommendation(s)

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