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Health difficulties in CdLS...

Para pais, prestadores de cuidados, prestadores de cuidados de saúde e professores, surgem frequentemente preocupações e questões relativas aos cuidados e bem-estar dos indivíduos com Cornelia de Lange syndrome.

Research shows that children and adults with CdLS tend to suffer from more health problems compared to other individuals with intellectual disability. The health difficulties that occur most frequently include eye problems, stomach/intestinal issues, genital problems and limb abnormalities.

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Blood Replenishment

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Anemia

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Anesthesia timeline

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Por favor note que o Pergunte ao perito service/ é composto por profissionais voluntários em várias áreas de foco. As respostas não são consideradas uma consulta médica, comportamental, ou educacional. Perguntar ao Perito não substitui os cuidados e atenção que o médico pessoal, psicólogo, consultor educacional, ou assistente social do seu filho pode prestar.

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Aprofunda os teus conhecimentos sobre Cornelia de Lange syndrome

Organizamos os nossos answers sobre Cornelia de Lange syndrome em tópicos. Pode navegar pelos nossos tópicos abaixo. Abaixo de cada tópico pode encontrar tópicos mais detalhados com answers que podem ser do seu interesse.

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Constipation

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Intestinal malrotation

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Reflux

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Senses

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The musculoskeletal system

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Sleep

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Autonomic nervous system

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Gastrointestinal Problems

Failed to execute template. Cause: [null]. Click on this message for details.

org.xwiki.rendering.RenderingException: Failed to execute renderer
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:287)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:843)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:805)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:792)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:747)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:739)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:79)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:73)
at org.xwiki.template.script.TemplateScriptService.render(TemplateScriptService.java:54)
at jdk.internal.reflect.GeneratedMethodAccessor268.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:566)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:218)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:95)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:222)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:177)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:138)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:843)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:805)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:792)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:747)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:739)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:79)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:73)
at org.xwiki.template.script.TemplateScriptService.render(TemplateScriptService.java:54)
at jdk.internal.reflect.GeneratedMethodAccessor268.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:566)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:218)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:190)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:95)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:222)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:177)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:138)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:843)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:805)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:785)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:771)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.render(DefaultTemplateManager.java:91)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.render(DefaultTemplateManager.java:85)
at com.xpn.xwiki.XWiki.evaluateTemplate(XWiki.java:2563)
at com.xpn.xwiki.web.Utils.parseTemplate(Utils.java:180)
at com.xpn.xwiki.web.XWikiAction.execute(XWikiAction.java:651)
at com.xpn.xwiki.web.XWikiAction.execute(XWikiAction.java:339)
at com.xpn.xwiki.web.LegacyActionServlet.service(LegacyActionServlet.java:114)
at javax.servlet.http.HttpServlet.service(HttpServlet.java:764)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:232)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at com.xpn.xwiki.web.ActionFilter.doFilter(ActionFilter.java:122)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.wysiwyg.filter.ConversionFilter.doFilter(ConversionFilter.java:61)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.container.servlet.filters.internal.SetHTTPHeaderFilter.doFilter(SetHTTPHeaderFilter.java:63)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.resource.servlet.RoutingFilter.doFilter(RoutingFilter.java:132)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.container.servlet.filters.internal.SavedRequestRestorerFilter.doFilter(SavedRequestRestorerFilter.java:208)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.container.servlet.filters.internal.SetCharacterEncodingFilter.doFilter(SetCharacterEncodingFilter.java:111)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:202)
at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:97)
at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:544)
at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:143)
at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:81)
at org.apache.catalina.valves.AbstractAccessLogValve.invoke(AbstractAccessLogValve.java:698)
at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:78)
at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:364)
at org.apache.coyote.http11.Http11Processor.service(Http11Processor.java:624)
at org.apache.coyote.AbstractProcessorLight.process(AbstractProcessorLight.java:65)
at org.apache.coyote.AbstractProtocol$ConnectionHandler.process(AbstractProtocol.java:831)
at org.apache.tomcat.util.net.NioEndpoint$SocketProcessor.doRun(NioEndpoint.java:1651)
at org.apache.tomcat.util.net.SocketProcessorBase.run(SocketProcessorBase.java:49)
at java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1128)
at java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:628)
at org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
at java.base/java.lang.Thread.run(Thread.java:829)
Caused by: org.xwiki.rendering.RenderingException: Failed to evaluate template with id [xwiki:XWiki.waihonapediaSkin^XWiki.XWikiSkinFileOverrideClass[3].content]
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:224)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:177)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:138)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
... 129 more
Caused by: org.xwiki.velocity.XWikiVelocityException: Failed to evaluate content with namespace [/skins/flamingo/view.vm]
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:289)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:95)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:222)
... 135 more
Caused by: org.apache.velocity.exception.MethodInvocationException: Invocation of method 'contains' in class java.lang.String threw exception java.lang.NullPointerException at /skins/flamingo/view.vm[line 194, column 29]
at org.apache.velocity.runtime.parser.node.ASTMethod.handleInvocationException(ASTMethod.java:308)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:235)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.evaluate(ASTReference.java:676)
at org.apache.velocity.runtime.parser.node.ASTOrNode.evaluate(ASTOrNode.java:106)
at org.apache.velocity.runtime.parser.node.ASTOrNode.evaluate(ASTOrNode.java:106)
at org.apache.velocity.runtime.parser.node.ASTExpression.evaluate(ASTExpression.java:65)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:169)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:218)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
... 138 more
Caused by: java.lang.NullPointerException